Author(s): Fernandes, Filipa Alexandra ; Oliveira, Paula A. ; Pinto, M.L. ; Venâncio, Carlos ; Félix, Luís ; Medeiros-Fonseca, Beatriz ; Correia, Rossana ; Prieto Lage, Miguel A. ; Ferreira, Isabel C.F.R. ; Barros, Lillian ; Heleno, Sandrina A.
Date: 2024
Persistent ID: http://hdl.handle.net/10198/30770
Origin: Biblioteca Digital do IPB
Subject(s): Plant-based beverage; Cyperus esculentus L.; In vivo safety assessment; FVB/N
This work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second experimental protocol, Group 3 consumed water and Group 4 consumed plant-based beverage for a limited time (4 h). Two experimental protocols were conducted to assess whether the exposure time to the beverage affects the animals’ physiological parameters, to determine if there is a possible daily limit for consumption of the product and to analyze their adverse effects. The mice consuming a beverage ingested a larger amount of drink and a smaller amount of food. Histologically there are no pathological changes in collected organs. The consumption of a plant-based beverage has been shown to have a positive effect on oxidative markers and can have a diuretic action. According to results, no behavioral changes or clinical signs of disease were observed throughout both experimental protocols, and no mortality was recorded.
