Author(s): Santiago, Helton da Costa ; Oliveira, Carolina Ferreira ; Santiago, Luciana ; Ferraz, Fernanda Oliveira ; Souza, Daniele da Glória de ; Freitas, Luiz Antônio Rodrigues de ; Afonso, Luís Carlos Crocco ; Teixeira, Mauro Martins ; Gazzinelli, Ricardo Tostes ; Vieira, Leda Quercia
Date: 2017
Origin: Oasisbr
The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.
