The use of next-generation sequencing in the study of monogenic obesity

• Autor(es): Serrasqueiro, Bernardo ; Veiga, Luísa ; Silva-Nunes, José ; Brito, Miguel
• Data: 2019
• Identificador Persistente: http://hdl.handle.net/10400.21/9759
• Origem: Repositório Científico do Instituto Politécnico de Lisboa
• Assunto(s): Next-generation sequencing; Monogenic obesity; DNA sequencing
• Tipo de Documento: Objeto de conferência
• Idioma: Inglês
• Contribuidor(es): RCIPL

Descrição

Technological innovation opens the possibility for scientific discovery, especially in biology and medicine, which allows the development of different perspectives that can bring a new understanding regarding different pathologies. Technologies such as the Next-Generation Sequencing (NGS) allow us not only to decode the human genome but also to describe and identify gene polymorphisms that lead to the development of diseases, as it happens with monogenic obesity. The aim of the study: Identify new mutations associated with monogenic obesity.