Detalhes do Documento

Synthetic biology to engineer bacteriophage genomes

Autor(es): Costa, Ana Rita ; Azeredo, Joana ; Pires, Diana Priscila Penso

Data: 2024

Identificador Persistente: https://hdl.handle.net/1822/91497

Origem: RepositóriUM - Universidade do Minho

Projeto/bolsa: info:eu-repo/grantAgreement/FCT/3599-PPCDT/EXPL%2FEMD-EMD%2F1142%2F2021/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04469%2F2020/PT;

Assunto(s): Bacteriophage; Bacteriophage engineering; YAC; BRED


Descrição

Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform.

FCT -Fundação para a Ciência e a Tecnologia(EXPL/EMD-EMD/1142/2021)

info:eu-repo/semantics/publishedVersion

Tipo de Documento Capitulo
Idioma Inglês
Contribuidor(es) Universidade do Minho
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