Document details

Synthetic biology to engineer bacteriophage genomes

Author(s): Costa, Ana Rita ; Azeredo, Joana ; Pires, Diana Priscila Penso

Date: 2024

Persistent ID: https://hdl.handle.net/1822/91497

Origin: RepositóriUM - Universidade do Minho

Project/scholarship: info:eu-repo/grantAgreement/FCT/3599-PPCDT/EXPL%2FEMD-EMD%2F1142%2F2021/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04469%2F2020/PT;

Subject(s): Bacteriophage; Bacteriophage engineering; YAC; BRED


Description

Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform.

FCT -Fundação para a Ciência e a Tecnologia(EXPL/EMD-EMD/1142/2021)

info:eu-repo/semantics/publishedVersion

Document Type Book part
Language English
Contributor(s) Universidade do Minho
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