How do Candida glabrata´s biofilms respond to antifungal drugs?

• Autor(es): Rodrigues, Célia Fortuna ; Rodrigues, E. ; Silva, Sónia Carina ; Azeredo, Joana ; Henriques, Mariana
• Data: 2015
• Identificador Persistente: https://hdl.handle.net/1822/37878
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): Candida glabrata; Biofilms; Resistance Mechanisms; Antifungals; Matrix
• Tipo de Documento: Outro
• Idioma: Inglês
• Contribuidor(es): Universidade do Minho

Descrição

Candida species are responsible for recurrent human infections, mostly in immunocompromised patients, due to their high vulnerability. Candida glabrata has been shown to have a major role in these infections being the second most prevalent species involved in human fungemia. Objective: To understand the effect of three different antifungal agents Fluconazole (Flu), Amphotericin B (AmB) and Caspofungin (Csf) - in C. glabratas biofilm formation, specially their role on matrix composition.