Genetically engineered silk-based composite biomaterials functionalized with fibronectin type-II that promote cell adhesion

• Author(s): Pereira, Ana Margarida Macedo Bernardes ; Machado, Raul ; Costa, André Manuel Abreu ; Ribeiro, Artur J. ; Collins, Tony ; Gomes, Andreia C ; Leonor, I. B. ; Kaplan, D.L. ; Reis, R. L. ; Casal, Margarida
• Date: 2016
• Persistent ID: https://hdl.handle.net/1822/46185
• Origin: RepositóriUM - Universidade do Minho
• Document Type: Other
• Language: English
• Contributor(s): Universidade do Minho

Description

[Excerpt] Recombinant protein-based polymers (rPBPs) are an emerging class of biopolymers inspired by Nature and produced by synthetic protein biotechnology approaches. Due to their exceptional physical-chemical and biological characteristics, as well as their ability to be customized for specific applications, rPBPs have been explored for the development of advanced biomaterials [1]. Within rPBPs, silk-like polymers (SLP) are being utilized in a range of studies in materials science [2]. [...]