Detalhes do Documento

Occupational exposure to formaldehyde: effects of years of exposure in the frequency of micronucleus

Autor(es): Ladeira, Carina ; Viegas, Susana ; Nunes, Carla ; Malta-Vacas, Joana ; Gomes, Mário ; Mendonça, Paula ; Prista, João ; Gomes, Manuel C. ; Brito, Miguel

Data: 2010

Identificador Persistente: http://hdl.handle.net/10400.21/665

Origem: Repositório Científico do Instituto Politécnico de Lisboa

Assunto(s): Anatomia patológica; Saúde ocupacional; Formaldeído; Factor de risco; Anatomia patológica; Anatomia patológica; Saúde ocupacional; Saúde ocupacional; Formaldeído; Formaldeído; Factor de risco; Factor de risco


Descrição

Formaldehyde: an important industrial compound used in the manufacture of synthetic resins and chemical compounds such as lubricants and adhesives; also applied as a disinfectant, preservative and in cosmetics productions; relevant workplace exposure to FA also occurs in anatomy, pathology and in mortuaries; classified by IARC as carcinogenic to humans (Group 1), based on sufficient evidence in humans and experimental animals; manifold in vitro studies indicated that FA can induce genotoxic effects in proliferating cultured mammalian cells. Aim of the study: to evaluate if years of exposure induced a genotoxic biomarkers increase, namely MN in lymphocytes and buccal cells, in workers occupationally exposed to FA (factory and pathology anatomy laboratory).

Tipo de Documento Objeto de conferência
Idioma Inglês
Contribuidor(es) RCIPL
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