Detalhes bibliográficos
| Resumo: | Intravenous IgG (ivIg) is a therapeutic alternative for lupus erythematosus, the mechanism of which remains to be fully understood. Here we investigated whether ivIg affects two established sub-phenotypes of SLE, namely relative oligoclonality of circulating T-cells and reduced activity of CD4 + Foxp3+ regulatory T-cells (Tregs) reflected by lower CD25 surface density. |
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| Autores principais: | Costa, Nuno |
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| Outros Autores: | Pires, Ana E.; Gabriel, Ana M.; Goulart, Luiz F.; Pereira, Clara; Leal, Bárbara; Queiros, Ana C.; Chaara, Wahiba; Moraes-Fontes, Maria F.; Vasconcelos, Carlos; Ferreira, Carlos; Martins, Jorge; Bastos, Marina; Santos, Maria J.; Pereira, Maria A.; Martins, Berta; Lima, Margarida; João, Cristina; Six, Adrien; Demengeot, Jocelyne; Fesel, Constantin |
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| Assunto: | Adult Forkhead Transcription Factors Humans Interleukin-2 Receptor alpha Subunit Longitudinal Studies Lupus Erythematosus, Systemic Middle Aged Receptors, Antigen, T-Cell, alpha-beta T-Lymphocyte Subsets T-Lymphocytes, Regulatory Young Adult Immunoglobulins, Intravenous |
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| Ano: | 2012 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Instituto Gulbenkian de Ciência |
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| Idioma: | inglês |
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| Origem: | ARCA - Access to Research and Communication Annals |
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