Detalhes bibliográficos
| Resumo: | The pol gene from HIV-2 infected patients from Cape Verde experiencing virologic failure was sequenced and drug resistance mutations were determined. Most patients were taking a first line regimen of AZT, 3TC and LPV/r. Resistance mutations were found in most patients (11/17, 64.7%) especially I82F (4/7, 57.1%) and M184 V (10/17, 58.8%). Resistance to all reverse transcriptase and protease inhibitors was found in 58.8% (10/17) of the patients. Integrase inhibitors are warranted to treat these patients. |
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| Autores principais: | Moranguinho, Inês |
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| Outros Autores: | Borrego, Pedro; Gonçalves, Fátima; Gomes, Perpétua; Rocha, José; Barreto, Jorge; Taveira, Nuno |
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| Assunto: | HIV-2 infected patients Genotypic resistance profiles Cape Verde Antiretroviral therapy |
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| Ano: | 2019 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Egas Moniz - Cooperativa de Ensino Superior, CRL |
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| Idioma: | inglês |
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| Origem: | Egas Moniz - Cooperativa de Ensino Superior, CRL |
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