Detalhes bibliográficos
| Resumo: | The progress in new delivery systems for active ingredients has boosted the dermopharmaceutical and cosmetic fields by allowing formulations to display enhanced skin permeation capabilities. Cyclodextrins (CDs) are cyclic oligosaccharides able to form host-guest inclusion complexes with guest active molecules, resulting in improved physicochemical properties of such molecules. The incorporation of CDs in dermopharmaceutical and cosmetics formulations has received much attention since the late 1970 s by enhancing modulation of the passage through the skin and vectorization into the target site while simultaneously offering a biocompatible delivery system. This paper features the advantages of CDs in dermopharmaceutical and cosmetic applications, such as the improvement of the apparent solubility and the stability of the active ingredients, the possibility of masking unpleasant odors, among others that are be described, emphasizing that these versatile skin active ingredient carriers are strongly promising both in the treatment of skin diseases and in the improvement of cosmetic formulations. |
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| Autores principais: | Ferreira, Laura |
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| Outros Autores: | Ferreira, Laura; Mascarenhas-Melo, Filipa; Melo, Filipa Mascarenhas; 0000-0003-0786-6280; ED15-0293-ADC7; staff; Rabaça, Sofia; Rabaça, Sofia; staff; Mathur, Ankita; Sharma, Ankur; Giram, Prabhanjan S.; Pawar, Kiran D.; Rahdar, Abbas; Raza, Faisal; Veiga, Francisco; Veiga, Francisco J. B.; Veiga, F. J.; Veiga, Francisco José B. Baptista; Veiga, Francisco J. B.; 0000-0002-1041-0068; 7113-9A34-499E; 35567448700; L-4884-2014; staff; Francisco Veiga is Full Professor of Faculty of Pharmacy of University of Coimbra and researcher at REQUIMTE LAQV Porto, Portugal. From 2012 to 2021, Francisco Veiga was director of Faculty of Pharmacy of University of Coimbra. His research team works currently in several projects, mainly focused on the development and characterisation of nanodelivery systems for targeted drug delivery. In 1996 he completed his doctorate research regarding characterisation of inclusion complexes formed by hydrophilic cyclodextrins (CD) and active pharmaceutical ingredients (APIs). His research is also conducted on the study of the inclusion complexes, in matrix systems and in the microencapsulation of peptide drugs for controlled drug release. Additionally, he has shown great interest to work in nano- and micro-carrier-based formulations for delivery and controlled release of drugs, such as microemulsions, nanotubes, ethosomes and micelleplexes. On this regard, Francisco Veiga is author or co-author of, 8 books, 28 book chapters, 257 journal articles, 2 patents, and 1 provisional application (h-index 56). Also, his willingness to teach, allowed him to guide tens of students in their activities of Doctorate Degree, Master Degree, and graduation final project. Professor Veiga is an invited member of the committee responsible for the assessment of medicines of Infarmed since 1997, and since 1998 an expert of the European Medicines Agency (EMA). He recently became a member of the Royal Academy of Galiza Pharmacy.; Mazzola, Priscila Gava; Paiva-Santos, Ana Cláudia; Paiva-Santos, Ana Cláudia; Santos, Ana Cláudia Paiva; 0000-0003-2710-6000; C214-55E1-D7BC; staff |
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| Assunto: | Active ingredient Cyclodextrin Cosmetic Dermopharmaceutical Skin |
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| Ano: | 2023 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade de Coimbra |
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| Idioma: | inglês |
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| Origem: | Estudo Geral - Universidade de Coimbra |
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