Publicação
O Biossensor Eletroquímico da Glicose na Diabetes Mellitus: do Auto-Teste à Monitorização Contínua
| Resumo: | Diabetes Mellitus (DM) is a chronic metabolic disease characterized by high blood glucose levels and classified into different types, including DM1 and DM2. It is currently facing an increasing global prevalence and is considered an “epidemic”; that requires appropriate control and prevention measures. Monitoring glucose levels plays a crucial role in the effective management of diabetes, allowing personalized treatment and detection of rapid changes in its plasma concentration.The remarkable development of glucose biosensors now provides a simple, fast and cost-effective solution for self-monitoring of glucose levels by diabetic patients. Electrochemical biosensors offer several advantages over other types, which has led to significant investment in their improvement and optimization of analytical performance.Continuous glucose monitoring (CGM) has demonstrated advantages over traditional self-monitoring (SMBG) in glycemic control in patients with DM1 or DM2. Insulin pumps and hybrid devices have improved glycemic control, improving quality of life and reducing the need for continuous glucose monitoring. In addition, artificial intelligence and big data play an essential role in analysis and decision-making in diabetes care, which requires careful attention to ethical and personal data protection.Despite significant advances in diabetes monitoring, the future lies in non-invasive approaches, including the development of wearable biosensors and the exploration of other biological fluids for glucose determination, to minimize the impact of invasive approaches on the quality of life of diabetic patients. |
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| Autores principais: | Alves, Pedro Alexandre Gomes |
| Assunto: | Diabetes Mellitus Epidemic Biosensors Traditional self-monitoring Continuous monitoring Diabetes Mellitus Epidemia Biossensores Auto-monitorização tradicional Monitorização contínua |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Coimbra |
| Idioma: | português |
| Origem: | Estudo Geral - Universidade de Coimbra |
| Resumo: | Diabetes Mellitus (DM) is a chronic metabolic disease characterized by high blood glucose levels and classified into different types, including DM1 and DM2. It is currently facing an increasing global prevalence and is considered an “epidemic”; that requires appropriate control and prevention measures. Monitoring glucose levels plays a crucial role in the effective management of diabetes, allowing personalized treatment and detection of rapid changes in its plasma concentration.The remarkable development of glucose biosensors now provides a simple, fast and cost-effective solution for self-monitoring of glucose levels by diabetic patients. Electrochemical biosensors offer several advantages over other types, which has led to significant investment in their improvement and optimization of analytical performance.Continuous glucose monitoring (CGM) has demonstrated advantages over traditional self-monitoring (SMBG) in glycemic control in patients with DM1 or DM2. Insulin pumps and hybrid devices have improved glycemic control, improving quality of life and reducing the need for continuous glucose monitoring. In addition, artificial intelligence and big data play an essential role in analysis and decision-making in diabetes care, which requires careful attention to ethical and personal data protection.Despite significant advances in diabetes monitoring, the future lies in non-invasive approaches, including the development of wearable biosensors and the exploration of other biological fluids for glucose determination, to minimize the impact of invasive approaches on the quality of life of diabetic patients. |
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