Publicação
Interest of X chromosome (Argus X-12 kit) in complex kinship analysis
| Resumo: | X-chromosomal short tandem repeats (X-STRs) have proven to be informative and useful in complex relationship testing. Paternity trio cases can most easily be solved with only autosomal STRs markers, while test of paternity duos involving more complex family relations could gain from X-chromosomal testing. The main goal of the present study was to investigate twelve X-STR markers (DXS7132, DXS7423, DXS8378, DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, and HPRTB) based on a Portuguese population sample, and their ability to solve complex kinship cases. Evaluations of statistical parameters of interest were also considered. |
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| Autores principais: | Cainé, Laura |
| Outros Autores: | Carvalho, Raquel; Costa, Sérgio; Pereira, Maria F.; Pinheiro, Maria F. |
| Assunto: | Forensic Genetics X-Chromosome Kinship |
| Ano: | 2011 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Instituto Nacional de Medicina Legal e Ciências Forenses, IP |
| Idioma: | inglês |
| Origem: | Instituto Nacional de Medicina Legal e Ciências Forenses, IP |
| Resumo: | X-chromosomal short tandem repeats (X-STRs) have proven to be informative and useful in complex relationship testing. Paternity trio cases can most easily be solved with only autosomal STRs markers, while test of paternity duos involving more complex family relations could gain from X-chromosomal testing. The main goal of the present study was to investigate twelve X-STR markers (DXS7132, DXS7423, DXS8378, DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, and HPRTB) based on a Portuguese population sample, and their ability to solve complex kinship cases. Evaluations of statistical parameters of interest were also considered. |
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