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Red blood cell dispersion in 100 μm glass capillaries: the temperature effect

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Detalhes bibliográficos
Resumo:The rheological behaviour of the red blood cells (RBCs) flowing in microvessels and microchannels depend on several effects, such as hematocrit (Hct), geometry, and temperature. Previous in vitro studies have measured the Hct effect on the radial dispersion (Dyy) at both diluted and concentrated suspensions of RBCs. However, according to our knowledge the effect of the temperature on RBC Dyy was never studied. Hence, the main purpose of the present work is to investigate the effect of the temperature on the RBC Dyy. In vitro human blood was pumped through a 100 μm glass capillary and by using a confocal micro-PTV system the RBC Dyy was calculated at two different temperatures, i.e., 25ºC and 37ºC.
Autores principais:Pinho, Diana
Outros Autores:Pereira, Ana I.; Lima, Rui A.; Ishikawa, Takuji; Imai, Yohsuke; Yamaguchi, Takami
Assunto:Radial dispersion Red blood cells Microcirculation
Ano:2010
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
Descrição
Resumo:The rheological behaviour of the red blood cells (RBCs) flowing in microvessels and microchannels depend on several effects, such as hematocrit (Hct), geometry, and temperature. Previous in vitro studies have measured the Hct effect on the radial dispersion (Dyy) at both diluted and concentrated suspensions of RBCs. However, according to our knowledge the effect of the temperature on RBC Dyy was never studied. Hence, the main purpose of the present work is to investigate the effect of the temperature on the RBC Dyy. In vitro human blood was pumped through a 100 μm glass capillary and by using a confocal micro-PTV system the RBC Dyy was calculated at two different temperatures, i.e., 25ºC and 37ºC.