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Diabetes mellitus therapy adherence and therapy characterization in Northeast Portugal: classical vs dipeptidyl peptidase iv (dpp-4) inhibitors

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Detalhes bibliográficos
Resumo:Diabetes mellitus is a chronic disease characterizes by the absence of insulin production by the body or the inability of their effectively use. Aim: To determine prevalence of diabetes types, the frequency of glycemic control, identify change in eating habits and physical activity, characterize the pharmacological therapy concerning classic and novel therapeutic approaches and verify the therapy adherence in diabetics of northeast Portugal. Methods: A cross-sectional study was performed by applying an interview to 202 adult diabetics of Trás-os-Montes region (Portugal), based on a questionnaire, with MAT scale (measure of adherence to therapy) validated for the Portuguese population. Results: The results showed 73,8% and 26,2% diabetics of type 2 and type 1, respectively. Most of the total diabetics (38,1%) have controlled the glycemic once a day, 60.4% have modified eating habits and 89.7% increased the frequency of physical activity. The drugs more used were metformin (63) and insulin (52) and the use of incretin mimetics was low (13.9%, 28), with more expression of the association of metformin and vildagliptin (21). The prevalence of diabetics adherents to therapy was 92,6%. Conclusions: The majority of diabetics adhered to pharmacological therapy and the use of dipeptidyl peptidase IV (DPP-4) inhibitors remains low.
Autores principais:Pereira, Daniela S.M.
Outros Autores:Saldanha, Daniela; Pires, Sandra; Pinto, Isabel C.; Pereira, Olívia R.
Assunto:Diabetes mellitus Therapy adherence Drugs therapy Metformin Dipeptidyl peptidase IV (DPP-4) inhibitors
Ano:2017
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
Descrição
Resumo:Diabetes mellitus is a chronic disease characterizes by the absence of insulin production by the body or the inability of their effectively use. Aim: To determine prevalence of diabetes types, the frequency of glycemic control, identify change in eating habits and physical activity, characterize the pharmacological therapy concerning classic and novel therapeutic approaches and verify the therapy adherence in diabetics of northeast Portugal. Methods: A cross-sectional study was performed by applying an interview to 202 adult diabetics of Trás-os-Montes region (Portugal), based on a questionnaire, with MAT scale (measure of adherence to therapy) validated for the Portuguese population. Results: The results showed 73,8% and 26,2% diabetics of type 2 and type 1, respectively. Most of the total diabetics (38,1%) have controlled the glycemic once a day, 60.4% have modified eating habits and 89.7% increased the frequency of physical activity. The drugs more used were metformin (63) and insulin (52) and the use of incretin mimetics was low (13.9%, 28), with more expression of the association of metformin and vildagliptin (21). The prevalence of diabetics adherents to therapy was 92,6%. Conclusions: The majority of diabetics adhered to pharmacological therapy and the use of dipeptidyl peptidase IV (DPP-4) inhibitors remains low.