Detalhes bibliográficos
| Resumo: | Different classes of stimuli-responsive smart hydrogels (SRSH) were synthesized in order to assess the usefulness of molecular imprinting and generation of interpenetrating polymer networks to obtain advanced materials with tailored properties/performance. Reversible Addition-Fragmentation Chain-Transfer (RAFT) polymerisation was exploited as an additional tool to increase the control on the formation process of these materials. Batch adsorption and frontal analysis (e.g. for 3-aminopyridine (3AMP) as depicted in the graphical abstract) techniques were used to quantify the affinity of different drugs with the produced SRSH. Stimulated drug release (e.g. due to temperature/pH changes) and protein immobilisation/release were also tested. Results obtained show that molecular imprinting and generation of interpenetrating networks are effective routes to obtain tailored materials with a particular affinity to selected template molecules. |
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| Autores principais: | Oliveira, Tânia |
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| Outros Autores: | Reitor, Patrícia; Oliveira, Daniela; Kadhirvel, Porkodi; Dias, Rolando; Costa, Mário Rui |
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| Assunto: | Molecular imprinting Interpenetrating polymers Stimuli-responsive Hydrogels |
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| Ano: | 2014 |
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| País: | Portugal |
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| Tipo de documento: | documento de conferência |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Instituto Politécnico de Bragança |
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| Idioma: | inglês |
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| Origem: | Biblioteca Digital do IPB |
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