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Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott

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Resumo:Rubus ulmifolius Schoot (Rosaceae), known as wild blackberry, is a perennial shrubfound in wild and cultivated habitats in Europe, Asia and North Africa[1]. Traditionally, R. ulmifoliusis considered to be anticatarrhal, antiseptic, diuretic, anti-inflammatory, antioxidant, astringent, and antispasmodic. Oral dosage forms are used for diarrhea, menstrual pain, menopause disorders, liver diseases, aphtha, gingivitis, hypertension and diabetes [2].Different classes of bioactive constituents are present in R. ulmifolius, including phenolic compounds. This study aimed to determine the phenolic composition of different preparations (decoction and hydromethanolic extract)of R. ulmifoliusflower buds. The analysis of phenolic compounds was carried out by reversed-phase high performance liquid chromatography coupled to diode array detection and mass spectrometry with electron spray ionization (HPLC-DAD-ESI/MS), in order to establish the specific phenolic profile of each preparation. The phenolic profile of both preparations was identical, varying only in the concentrations found. Twenty-three phenolic compounds were identified in both samples, in which seven were identified as phenolic acids (di- and caffeolyqui nic, p-coumaroylquinicand feruloylquinic acids),ten flavonoids (quercetin and kaempferol derivatives and catechin), and five ellagitannin derivatives (lambertianin and di -HHDP-galloyl glucose). These compoundswere found in both preparations. The most abundant compounds foundwere ellagitannin derivatives, such as lambertianin and di-HHDP-galloyl glucose. Gasperotti et al. [3]have identified these compounds in R. fruticosus fruits. To our knowledge, this is the first time that these compounds were identified and quantified inR. ulmifolius flowers buds.
Autores principais:Martins, Ana
Outros Autores:Barros, Lillian; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.
Ano:2013
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Martins, Ana
author2 Barros, Lillian
Dueñas, Montserrat
Carvalho, Ana Maria
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
author2_role author
author
author
author
author
author_facet Martins, Ana
Barros, Lillian
Dueñas, Montserrat
Carvalho, Ana Maria
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Martins, Ana\"},{\"Person.name\":\"Barros, Lillian\",\"Person.identifier.orcid\":\"0000-0002-9050-5189\"},{\"Person.name\":\"Dueñas, Montserrat\"},{\"Person.name\":\"Carvalho, Ana Maria\",\"Person.identifier.orcid\":\"0000-0001-5508-5935\"},{\"Person.name\":\"Santos-Buelga, Celestino\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Martins, Ana
Barros, Lillian
Dueñas, Montserrat
Carvalho, Ana Maria
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
datacite.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2013-09-09T09:43:15Z
datacite.date.embargoed.fl_str_mv 2013-09-09T09:43:15Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.titles.title.fl_str_mv Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Martins, Ana
Barros, Lillian
Dueñas, Montserrat
Carvalho, Ana Maria
Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
dc.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
dc.date.available.fl_str_mv 2013-09-09T09:43:15Z
dc.date.embargoed.fl_str_mv 2013-09-09T09:43:15Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/8662
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.title.fl_str_mv Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_c94f
description Rubus ulmifolius Schoot (Rosaceae), known as wild blackberry, is a perennial shrubfound in wild and cultivated habitats in Europe, Asia and North Africa[1]. Traditionally, R. ulmifoliusis considered to be anticatarrhal, antiseptic, diuretic, anti-inflammatory, antioxidant, astringent, and antispasmodic. Oral dosage forms are used for diarrhea, menstrual pain, menopause disorders, liver diseases, aphtha, gingivitis, hypertension and diabetes [2].Different classes of bioactive constituents are present in R. ulmifolius, including phenolic compounds. This study aimed to determine the phenolic composition of different preparations (decoction and hydromethanolic extract)of R. ulmifoliusflower buds. The analysis of phenolic compounds was carried out by reversed-phase high performance liquid chromatography coupled to diode array detection and mass spectrometry with electron spray ionization (HPLC-DAD-ESI/MS), in order to establish the specific phenolic profile of each preparation. The phenolic profile of both preparations was identical, varying only in the concentrations found. Twenty-three phenolic compounds were identified in both samples, in which seven were identified as phenolic acids (di- and caffeolyqui nic, p-coumaroylquinicand feruloylquinic acids),ten flavonoids (quercetin and kaempferol derivatives and catechin), and five ellagitannin derivatives (lambertianin and di -HHDP-galloyl glucose). These compoundswere found in both preparations. The most abundant compounds foundwere ellagitannin derivatives, such as lambertianin and di-HHDP-galloyl glucose. Gasperotti et al. [3]have identified these compounds in R. fruticosus fruits. To our knowledge, this is the first time that these compounds were identified and quantified inR. ulmifolius flowers buds.
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funding.funder.alternateName_str_mv FCT
funding.funder.identifier_str_mv http://doi.org/10.13039/501100001871
funding.funder.name_str_mv Fundação para a Ciência e a Tecnologia
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oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/8662
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person_str_mv Martins, Ana
Barros, Lillian
Barros, Lillian
https://www.ciencia-id.pt/9616-35CB-D001
9616-35CB-D001
http://orcid.org/0000-0002-9050-5189
0000-0002-9050-5189
Dueñas, Montserrat
Carvalho, Ana Maria
Carvalho, Ana Maria
https://www.ciencia-id.pt/D31A-35AF-E2A9
D31A-35AF-E2A9
http://orcid.org/0000-0001-5508-5935
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Santos-Buelga, Celestino
Ferreira, Isabel C.F.R.
Ferreira, Isabel C.F.R.
https://www.ciencia-id.pt/9418-CF95-9919
9418-CF95-9919
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spelling engporRubus ulmifolius Schoot (Rosaceae), known as wild blackberry, is a perennial shrubfound in wild and cultivated habitats in Europe, Asia and North Africa[1]. Traditionally, R. ulmifoliusis considered to be anticatarrhal, antiseptic, diuretic, anti-inflammatory, antioxidant, astringent, and antispasmodic. Oral dosage forms are used for diarrhea, menstrual pain, menopause disorders, liver diseases, aphtha, gingivitis, hypertension and diabetes [2].Different classes of bioactive constituents are present in R. ulmifolius, including phenolic compounds. This study aimed to determine the phenolic composition of different preparations (decoction and hydromethanolic extract)of R. ulmifoliusflower buds. The analysis of phenolic compounds was carried out by reversed-phase high performance liquid chromatography coupled to diode array detection and mass spectrometry with electron spray ionization (HPLC-DAD-ESI/MS), in order to establish the specific phenolic profile of each preparation. The phenolic profile of both preparations was identical, varying only in the concentrations found. Twenty-three phenolic compounds were identified in both samples, in which seven were identified as phenolic acids (di- and caffeolyqui nic, p-coumaroylquinicand feruloylquinic acids),ten flavonoids (quercetin and kaempferol derivatives and catechin), and five ellagitannin derivatives (lambertianin and di -HHDP-galloyl glucose). These compoundswere found in both preparations. The most abundant compounds foundwere ellagitannin derivatives, such as lambertianin and di-HHDP-galloyl glucose. Gasperotti et al. [3]have identified these compounds in R. fruticosus fruits. To our knowledge, this is the first time that these compounds were identified and quantified inR. ulmifolius flowers buds.application/pdfporPhenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius SchottMartins, AnaPersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801Dueñas, MontserratPersonalCarvalho, Ana MariaDSpacehttp://dspace.org/items/977f5254-f7c5-4c91-873f-2700ecd4692fDSpacehttp://dspace.org/items/977f5254-f7c5-4c91-873f-2700ecd4692fCarvalhoAna MariaCiência IDhttps://www.ciencia-id.ptD31A-35AF-E2A9ORCIDhttp://orcid.org0000-0001-5508-5935Scopus Author IDhttps://www.scopus.com20336503900Santos-Buelga, CelestinoPersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.pt2013-09-09T09:43:15Z20132013-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/8662http://purl.org/coar/access_right/c_abf2open access485703 bytesFundação para a Ciência e a TecnologiaStrategic Project - UI 690 - 2011-20126817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871other research producthttp://purl.org/coar/resource_type/c_c94fconference objecthttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/a950ed43-5861-47e5-9242-a0248fb7d50d/download1st Symposium on Medicinal Chemistry of University of MinhoBraga, Portugal
spellingShingle Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
Martins, Ana
status SINGLETON
title Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
title_full Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
title_fullStr Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
title_full_unstemmed Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
title_short Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
title_sort Phenolic profile of hydromethanolic extract and decoction of Rubus ulmifolius Schott
url http://hdl.handle.net/10198/8662
visible 1