Publicação
Valorization of rambutan (Nephelium lappaceum L.) peel: chemical composition, biological activity, and optimized recovery of anthocyanins
| Resumo: | Chemical constituents and bioactive properties of rambutan (Nephelium lappaceum L.) peel were characterized and heat-/ultrasound-assisted extractions (HAE/UAE) of anthocyanins were optimized by response surface methodology. Five organic acids, the alpha-, gamma-, and delta-tocopherol isoforms, and twenty-five fatty acids (36.8 % oleic acid) were identified, as well as a phenolic profile composed of ellagitannin derivatives, geraniin isomers, ellagic acid, and delphinidin-O derivatives. The extract showed antioxidant activity via lipid peroxidation (IC50 = 2.79 +/- 0.03 mu g/mL) and oxidative hemolysis (IC50 = 72 +/- 2 mu g/mL) inhibition, and displayed antibacterial and antifungal properties (MIC <= 1 mg/mL). On the other hand, no cytotoxicity was observed in tumor and non -tumor cell lines up to 400 mu g/mL. The recovery of anthocyanins was more effective using HAE than UAE, allowing greater yields (16.2 mg/g extract) in just 3 min and using lower ethanol proportions. Overall, rambutan peel could be upcycled into bioactive ingredients and natural colorants for industrial applications. |
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| Autores principais: | Albuquerque, Bianca R. |
| Outros Autores: | Pinela, José; Dias, Maria Inês; Pereira, Carla; Petrović, Jovana; Soković, Marina; Calhelha, Ricardo C.; Oliveira, Beatriz; Ferreira, Isabel C.F.R.; Barros, Lillian |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| Resumo: | Chemical constituents and bioactive properties of rambutan (Nephelium lappaceum L.) peel were characterized and heat-/ultrasound-assisted extractions (HAE/UAE) of anthocyanins were optimized by response surface methodology. Five organic acids, the alpha-, gamma-, and delta-tocopherol isoforms, and twenty-five fatty acids (36.8 % oleic acid) were identified, as well as a phenolic profile composed of ellagitannin derivatives, geraniin isomers, ellagic acid, and delphinidin-O derivatives. The extract showed antioxidant activity via lipid peroxidation (IC50 = 2.79 +/- 0.03 mu g/mL) and oxidative hemolysis (IC50 = 72 +/- 2 mu g/mL) inhibition, and displayed antibacterial and antifungal properties (MIC <= 1 mg/mL). On the other hand, no cytotoxicity was observed in tumor and non -tumor cell lines up to 400 mu g/mL. The recovery of anthocyanins was more effective using HAE than UAE, allowing greater yields (16.2 mg/g extract) in just 3 min and using lower ethanol proportions. Overall, rambutan peel could be upcycled into bioactive ingredients and natural colorants for industrial applications. |
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