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Conjugate additions of carbon nucleophiles to chromone derivatives towards nitrogen heterocycles

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Detalhes bibliográficos
Resumo:Conjugate additions of nitromethane to the extended π- system of chromone derivatives afforded the 1,6-conjugate addition products, together with structure complex oxygen heterocycles through tandem processes. Further functionalization of targeted adducts allowed the preparation of biological relevant nitrogen heterocycles such as styrylpyrrolidines, as well as pyrazole and bis-pyrazole derivatives.
Autores principais:Albuquerque, Hélio
Outros Autores:Santos, Clementina M.M.; Cavaleiro, José; Silva, Artur
Ano:2017
País:Portugal
Tipo de documento:póster em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
Descrição
Resumo:Conjugate additions of nitromethane to the extended π- system of chromone derivatives afforded the 1,6-conjugate addition products, together with structure complex oxygen heterocycles through tandem processes. Further functionalization of targeted adducts allowed the preparation of biological relevant nitrogen heterocycles such as styrylpyrrolidines, as well as pyrazole and bis-pyrazole derivatives.