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Motions of particles and red blood cells in a bifurcation: comparison between experiments and numerical simulations

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Detalhes bibliográficos
Resumo:The blood flow dynamics in microcirculation depends strongly on the microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations. This paper presents the application of a confocal micro-PTV system to track RBCs through a rectangular polydimethysiloxane (PDMS) microchannel with a bifurcation. By using a confocal micro-PTV system, we have measured the effect of bifurcation on the flow behaviour of both fluorescent particles diluted in pure water and RBCs in concentrated suspensions. After performing simulations with the commercial finite element software package POLYFLOW®, some experimental results were compared with the numerical results. Our preliminary qualitative results suggest that the in vitro blood flowing (Re = 0.007) through a bifurcation seems to have a tendency to behave more closely as a Power law model than as a Carreau or Newtonian model.
Autores principais:Lagoela, Marco
Outros Autores:Oliveira, Brigitte; Cidre, Diana; Fernandes, Carla S.; Balsa, Carlos; Lima, Rui A.; Dias, Ricardo P.; Ishikawa, Takuji; Imai, Yohsuke; Yamaguchi, Takami
Assunto:Blood Flow Microchannel Bifurcation Microcirculation
Ano:2009
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
Descrição
Resumo:The blood flow dynamics in microcirculation depends strongly on the microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations. This paper presents the application of a confocal micro-PTV system to track RBCs through a rectangular polydimethysiloxane (PDMS) microchannel with a bifurcation. By using a confocal micro-PTV system, we have measured the effect of bifurcation on the flow behaviour of both fluorescent particles diluted in pure water and RBCs in concentrated suspensions. After performing simulations with the commercial finite element software package POLYFLOW®, some experimental results were compared with the numerical results. Our preliminary qualitative results suggest that the in vitro blood flowing (Re = 0.007) through a bifurcation seems to have a tendency to behave more closely as a Power law model than as a Carreau or Newtonian model.