Publicação
Synthesis of 7-aryl or heteroarylamino-2,3-dimethylbenzo[b]thiophenes by palladium-catalyzed C-N cross coupling and anti-oxidant activity studies
| Resumo: | ln recent years we have been interested in the synthesis of diarylamines in the benzo[b]thiophene series functionalizing either the benzene or the thiophene2 ring. Here we describe the synthesis of new 7-aryl or heteroarylamino-2,3-dimethylbenzo[b]thiophenes, reacting, the also prepared 7-bromo or 7-amino-2,3-climethylbenzo[b]thiophenes with anilines and 3-aminopyridine or bromobenzenes anel 2-bromopyridine, respectively, under palladium-catalyzed C-N cross-coupling conditions (Scheme). |
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| Autores principais: | Calhelha, Ricardo C. |
| Outros Autores: | Ferreira, Isabel C.F.R.; Estevinho, Leticia M.; Queiroz, Maria João R.P. |
| Ano: | 2005 |
| País: | Portugal |
| Tipo de documento: | documento de conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| Resumo: | ln recent years we have been interested in the synthesis of diarylamines in the benzo[b]thiophene series functionalizing either the benzene or the thiophene2 ring. Here we describe the synthesis of new 7-aryl or heteroarylamino-2,3-dimethylbenzo[b]thiophenes, reacting, the also prepared 7-bromo or 7-amino-2,3-climethylbenzo[b]thiophenes with anilines and 3-aminopyridine or bromobenzenes anel 2-bromopyridine, respectively, under palladium-catalyzed C-N cross-coupling conditions (Scheme). |
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