Detalhes bibliográficos
| Resumo: | A simple and sensitive method that allows the simultaneous detection of single or multiple cancer biomarkers is envisaged and may be an important tool in cancer diagnosis. Osteopontin (OPN) is a protein that is present in several body fluids and has been reported as a possible cancer biomarker. The voltammetric signals generated by the dual-aptasensor array, after the formation of the aptamers-protein complex, were monitored using cyclic voltammetry (CV) and square-wave voltammetry (SWV), using [Fe(CN)6] 3/ 4 as a redox probe. The aim of this work is to optimize the experimental conditions to development a label-free voltammetric dual-aptasensor array for the detection of human osteopontin using a 2k factorial experimental design. |
| Autores principais: | Meirinho, Sofia G. |
| Outros Autores: | Ezziddine, Maha; Veloso, Ana C.A.; Dias, L.G.; Rodrigues, Lígia R.; Othmane, Ali; Peres, António M. |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | póster em conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |