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An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

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Bibliographic Details
Summary:Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.
Main Authors:Mesquita, Mariana Q.
Other Authors:Dias, Cristina J.; Gamelas, Sara; Fardilha, Margarida; Neves, Maria G. P. M. S.; Faustino, Maria Amparo F.
Subject:Photodynamic therapy Drug delivery Liposomes Silica nanoparticles Gold nanoparticles Polymeric micelles
Year:2018
Country:Portugal
Document type:article
Access type:open access
Associated institution:Universidade de Aveiro
Language:English
Origin:RIA - Repositório Institucional da Universidade de Aveiro
Description
Summary:Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.