Publicação
An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy
| Resumo: | Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment. |
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| Autores principais: | Mesquita, Mariana Q. |
| Outros Autores: | Dias, Cristina J.; Gamelas, Sara; Fardilha, Margarida; Neves, Maria G. P. M. S.; Faustino, Maria Amparo F. |
| Assunto: | Photodynamic therapy Drug delivery Liposomes Silica nanoparticles Gold nanoparticles Polymeric micelles |
| Ano: | 2018 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Aveiro |
| Idioma: | inglês |
| Origem: | RIA - Repositório Institucional da Universidade de Aveiro |
| Resumo: | Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment. |
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