Publicação
Hydrothermal Synthesis and Appraisal of Mg-Doped Hydroxyapatite Nanopowders
| Resumo: | Nano rods of magnesium-doped hydroxyapatite, Ca10-xMgx(PO4)(6)(OH)(2)(Mg-x-HA, x = 0-1.0), were successfully synthesized through cetyltrimethyl ammonium bromide assisted hydrothermal synthesis method. X-ray diffraction, infrared spectroscopy, thermogravimetric analysis and transmission electron microscopy, provided experimental evidences about the effects of Mg-doping on the phase assemblage, crystallite size, morphology, specific surface area of Mg-doped hydroxyapatite nanopowders. The replacement Ca2+ ions by smaller Mg2+ ones caused lattice shrinkage and lattice strains that enhanced the solubility and the in vitro bio-mineralisation activity upon immersing sintered samples in simulated body fluid. The severity of these structural changes rose with increasing Mg-doping and enable tailoring the in vitro biological activity enabling selecting the most suitable material for bone grafts and tissue engineering applications. |
|---|---|
| Autores principais: | Bricha, Meriame |
| Outros Autores: | Belmamouni, Younes; Essassi, El Mokhtar; Ferreira, Jose M. F.; El Mabrouk, Khalil |
| Assunto: | MAGNESIUM-SUBSTITUTED HYDROXYAPATITE TRICALCIUM PHOSPHATE DRUG-DELIVERY IN-VITRO CALCIUM ORTHOPHOSPHATES BIOMEDICAL APPLICATIONS THERMAL-BEHAVIOR AQUEOUS-MEDIUM BONE NANOPARTICLES |
| Ano: | 2013 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Aveiro |
| Idioma: | inglês |
| Origem: | RIA - Repositório Institucional da Universidade de Aveiro |
| Resumo: | Nano rods of magnesium-doped hydroxyapatite, Ca10-xMgx(PO4)(6)(OH)(2)(Mg-x-HA, x = 0-1.0), were successfully synthesized through cetyltrimethyl ammonium bromide assisted hydrothermal synthesis method. X-ray diffraction, infrared spectroscopy, thermogravimetric analysis and transmission electron microscopy, provided experimental evidences about the effects of Mg-doping on the phase assemblage, crystallite size, morphology, specific surface area of Mg-doped hydroxyapatite nanopowders. The replacement Ca2+ ions by smaller Mg2+ ones caused lattice shrinkage and lattice strains that enhanced the solubility and the in vitro bio-mineralisation activity upon immersing sintered samples in simulated body fluid. The severity of these structural changes rose with increasing Mg-doping and enable tailoring the in vitro biological activity enabling selecting the most suitable material for bone grafts and tissue engineering applications. |
|---|