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Does surface charge play a role in nanoparticulate-systems toxicity?

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Detalhes bibliográficos
Resumo:The aim of the present work was to compare the toxicity of relevant biomedical acrylic based particulate systems (polymethylmethacrylate – PMMA), with different charges, within the same size range (500nm). Specifically, PMMA (negatively charged) and PMMA-Eudragit (positively charged) formulations were considered.
Autores principais:Bettencourt, A.
Outros Autores:Graça, D.F.; Ferreira, IFS; Matos, A.; Louro, Henriqueta; Silva, Maria João; Almeida, A.J.; Gonçalves, L.M.
Assunto:Genotoxicidade Ambiental Nanomateriais Nanotecnologia PMMA Toxicity Nanomaterials Nanotoxicology
Ano:2015
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Nacional de Saúde Doutor Ricardo Jorge
Idioma:inglês
Origem:Repositório Científico do Instituto Nacional de Saúde
Descrição
Resumo:The aim of the present work was to compare the toxicity of relevant biomedical acrylic based particulate systems (polymethylmethacrylate – PMMA), with different charges, within the same size range (500nm). Specifically, PMMA (negatively charged) and PMMA-Eudragit (positively charged) formulations were considered.