Publicação

Recent advances on antimicrobial wound dressing: A review

Ver documento

Detalhes bibliográficos
Resumo:Skin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrobial agents emerged as viable options to reduce wound bacterial colonization and infection, in order to improve the healing process. In this review, an overview of the most prominent antibacterial agents incorporated in wound dressings along with their mode of action is provided. Furthermore, the recent advances in the therapeutic approaches used in the clinic and some future perspectives regarding antibacterial wound dressings are also discussed.
Autores principais:Simões, Déborah
Outros Autores:Miguel, Sónia; Ribeiro, Maximiano; Coutinho, Paula; Mendonça, António; Correia, Ilídio
Assunto:Antibiotics Antimicrobial wound dressings Nanoparticles Natural products Skin and soft tissue infections Wound healing
Ano:2018
País:Portugal
Tipo de documento:livro
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico da Guarda
Idioma:inglês
Origem:Repositório Institucional do Instituto Politécnico da Guarda
Descrição
Resumo:Skin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrobial agents emerged as viable options to reduce wound bacterial colonization and infection, in order to improve the healing process. In this review, an overview of the most prominent antibacterial agents incorporated in wound dressings along with their mode of action is provided. Furthermore, the recent advances in the therapeutic approaches used in the clinic and some future perspectives regarding antibacterial wound dressings are also discussed.