Publicação
Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
| Resumo: | Aging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality. |
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| Autores principais: | Pêgo, José M. |
| Outros Autores: | Morgado, Pedro; Cerqueira, João José; Almeida, O. F. X.; Sousa, Nuno |
| Assunto: | Acoustic Stimulation Age Factors Amygdala Animals Anxiety Behavior, Animal Cell Count Dose-Response Relationship, Radiation Male Maze Learning Neurons Rats Rats, Wistar Reflex, Startle Septal Nuclei Stereotaxic Techniques Aging BNST Stereology BLAST |
| Ano: | 2006 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | Aging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality. |
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