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Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis

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Summary:Aging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality.
Main Authors:Pêgo, José M.
Other Authors:Morgado, Pedro; Cerqueira, João José; Almeida, O. F. X.; Sousa, Nuno
Subject:Acoustic Stimulation Age Factors Amygdala Animals Anxiety Behavior, Animal Cell Count Dose-Response Relationship, Radiation Male Maze Learning Neurons Rats Rats, Wistar Reflex, Startle Septal Nuclei Stereotaxic Techniques Aging BNST Stereology BLAST
Year:2006
Country:Portugal
Document type:article
Access type:restricted access
Associated institution:Universidade do Minho
Language:English
Origin:RepositóriUM - Universidade do Minho
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author Pêgo, José M.
author2 Morgado, Pedro
Cerqueira, João José
Almeida, O. F. X.
Sousa, Nuno
author2_role author
author
author
author
author_facet Pêgo, José M.
Morgado, Pedro
Cerqueira, João José
Almeida, O. F. X.
Sousa, Nuno
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Pêgo, José M.\"},{\"Person.name\":\"Morgado, Pedro\"},{\"Person.name\":\"Cerqueira, João José\"},{\"Person.name\":\"Almeida, O. F. X.\"},{\"Person.name\":\"Sousa, Nuno\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Pêgo, José M.
Morgado, Pedro
Cerqueira, João José
Almeida, O. F. X.
Sousa, Nuno
datacite.date.Accepted.fl_str_mv 2006-10-16T00:00:00Z
datacite.date.embargoed.fl_str_mv 10000-01-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
datacite.titles.title.fl_str_mv Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Pêgo, José M.
Morgado, Pedro
Cerqueira, João José
Almeida, O. F. X.
Sousa, Nuno
dc.date.Accepted.fl_str_mv 2006-10-16T00:00:00Z
dc.date.embargoed.fl_str_mv 10000-01-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/64292
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
dc.title.fl_str_mv Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Aging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality.
dirty 0
eu_rights_str_mv restrictedAccess
format article
fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/04a226b0-0854-42ec-91ed-ecefc848be96/download
id rum_097efdc754d135e85a249c8a940264bc
identifier.url.fl_str_mv https://hdl.handle.net/1822/64292
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/64292
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Pêgo, José M.
Morgado, Pedro
Cerqueira, João José
Almeida, O. F. X.
Sousa, Nuno
publishDate 2006
publisher.none.fl_str_mv Elsevier
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevierporAging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality.application/pdfporMismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalisPêgo, José M.Morgado, PedroCerqueira, João JoséAlmeida, O. F. X.Sousa, NunoHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0166-4328DOIIsPartOf10.1016/j.bbr.2006.06.0352006-10-1610000-01-01T00:00:00Z2006-10-16T00:00:00ZHandlehttps://hdl.handle.net/1822/64292http://purl.org/coar/access_right/c_16ecrestricted accessAcoustic StimulationAge FactorsAmygdalaAnimalsAnxietyBehavior, AnimalCell CountDose-Response Relationship, RadiationMaleMaze LearningNeuronsRatsRats, WistarReflex, StartleSeptal NucleiStereotaxic TechniquesAgingBNSTStereologyBLAST330968 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_f1cfapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/04a226b0-0854-42ec-91ed-ecefc848be96/download
spellingShingle Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
Pêgo, José M.
Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
status SINGLETON
subject.fl_str_mv Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
title Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
title_full Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
title_fullStr Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
title_full_unstemmed Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
title_short Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
title_sort Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis
topic Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
topic_facet Acoustic Stimulation
Age Factors
Amygdala
Animals
Anxiety
Behavior, Animal
Cell Count
Dose-Response Relationship, Radiation
Male
Maze Learning
Neurons
Rats
Rats, Wistar
Reflex, Startle
Septal Nuclei
Stereotaxic Techniques
Aging
BNST
Stereology
BLAST
url https://hdl.handle.net/1822/64292
visible 1