Publicação
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization
| Resumo: | Neat and hybrid poly(2-pyrrolidone), i.e. polyamide 4 (PA4) microparticles containing magnetic or conductive metal, metal oxide, or carbon nanotube fillers were prepared via environmentally-friendly solventless activated ring-opening polymerization of 2-pyrrolidone at 40 C. The method produces high porosity microparticles with diameters of 5e12mm and conversion to PA4 of 56e65%. Their structure and properties were characterized by light- and electron microscopy, thermal, spectral and X-ray diffraction techniques. Two crystalline polymorphs, namelya andb PА4, were found to coexist at room temperature by X-ray diffraction. The assessment of the adsorption capacity of the PA4 hybrid microparticles toward model protein showed up to 60% efficiency only after 1 h of incubation without any preliminary activation or functionalization. |
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| Autores principais: | Dencheva, Nadya Vasileva |
| Outros Autores: | Braz, Joana Filipa Barros; Nunes, Teresa G.; Oliveira, Filipa D.; Denchev, Z. |
| Assunto: | Polyamide 4 2-Pyrrolidone Anionic ring-opening polymerization Magnetic microparticles Protein carriers |
| Ano: | 2018 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | Neat and hybrid poly(2-pyrrolidone), i.e. polyamide 4 (PA4) microparticles containing magnetic or conductive metal, metal oxide, or carbon nanotube fillers were prepared via environmentally-friendly solventless activated ring-opening polymerization of 2-pyrrolidone at 40 C. The method produces high porosity microparticles with diameters of 5e12mm and conversion to PA4 of 56e65%. Their structure and properties were characterized by light- and electron microscopy, thermal, spectral and X-ray diffraction techniques. Two crystalline polymorphs, namelya andb PА4, were found to coexist at room temperature by X-ray diffraction. The assessment of the adsorption capacity of the PA4 hybrid microparticles toward model protein showed up to 60% efficiency only after 1 h of incubation without any preliminary activation or functionalization. |
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