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Lipase-catalysed polymerization of eutectic mixtures

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Resumo:Aiming to reduce the toxicity and operational costs often associated to chemical processes, the enzymatic synthesis is applied herein as a sustainable route for producing polyesters. The use of NADES components as a source of monomers for the synthesis of polymers through lipase-catalysed esterification in an anhydrous medium is detailed for the first time. Three NADES composed by glycerol and an organic base, or acid, were used to produce polyesters, through polymerization reactions catalysed by Aspergillus oryzae lipase. High polyester conversion rates (above 70 \%), containing at least 20 monomeric units (glycerol: organic acid/base (1:1)), were observed by MALDI-TOF analysis. The NADES monomers' capacity for polymerization, along with their non-toxicity, cheap cost, and simplicity of production, sets up these solvents as a greener and cleaner approach for the synthesis of high value-added products.
Autores principais:Freitas, David
Outros Autores:Quesado, Vânia; Rocha, Diana; Noro, Jennifer Martins; Martins, Madalena; Cavaco-Paulo, Artur; Silva, C.
Assunto:lipase NADES (natural deep eutectic solvents) polymerization polyesters enzymatic catalysis natural deep eutectic solvents
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Aiming to reduce the toxicity and operational costs often associated to chemical processes, the enzymatic synthesis is applied herein as a sustainable route for producing polyesters. The use of NADES components as a source of monomers for the synthesis of polymers through lipase-catalysed esterification in an anhydrous medium is detailed for the first time. Three NADES composed by glycerol and an organic base, or acid, were used to produce polyesters, through polymerization reactions catalysed by Aspergillus oryzae lipase. High polyester conversion rates (above 70 \%), containing at least 20 monomeric units (glycerol: organic acid/base (1:1)), were observed by MALDI-TOF analysis. The NADES monomers' capacity for polymerization, along with their non-toxicity, cheap cost, and simplicity of production, sets up these solvents as a greener and cleaner approach for the synthesis of high value-added products.