Publicação
HPLC purification and structural characterization by NMR spectroscopy and mass spectrometry of Peptaibolin mimetics
| Resumo: | This work presents our study of optimization of P-HPLC conditions to obtain pure peptaibol mimetics, to be used in biological activity studies. After purification, the sequence and structure of the peptides obtained were confirmed by NMR spectroscopy (1H, 13C, DEPT, HMBC and HMQC spectra) and mass spectrometry. |
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| Autores principais: | Castro, Vânia I. B. |
| Outros Autores: | Carvalho, Carina Martins; Costa, Susana P. G.; Lima, Sílvia M. M. A. Pereira |
| Assunto: | Peptide NMR spectroscopy Mass spectrometry HPLC purification |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | This work presents our study of optimization of P-HPLC conditions to obtain pure peptaibol mimetics, to be used in biological activity studies. After purification, the sequence and structure of the peptides obtained were confirmed by NMR spectroscopy (1H, 13C, DEPT, HMBC and HMQC spectra) and mass spectrometry. |
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