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Terra is a left–right asymmetry gene required for left–right synchronization of the segmentation clock

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Detalhes bibliográficos
Resumo:To establish the vertebrate body plan, it is fundamental to create left–right asymmetry in the lateral-plate mesoderm to correctly position the organs. However, it is also crucial to maintain symmetry between the left and the right sides of the presomitic mesoderm, ensuring the allocation of symmetrical body structures, such as the axial skeleton and skeletal muscles. Here, we show that terra is an early left-sided expressed gene that links left–right patterning with bilateral synchronization of the segmentation clock.
Autores principais:Saúde, Leonor
Outros Autores:Lourenço, Raquel; Gonçalves, Alexandre; Palmeirim, I.
Assunto:Terra Left–right asymmetry Segmentation clock
Ano:2005
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:To establish the vertebrate body plan, it is fundamental to create left–right asymmetry in the lateral-plate mesoderm to correctly position the organs. However, it is also crucial to maintain symmetry between the left and the right sides of the presomitic mesoderm, ensuring the allocation of symmetrical body structures, such as the axial skeleton and skeletal muscles. Here, we show that terra is an early left-sided expressed gene that links left–right patterning with bilateral synchronization of the segmentation clock.