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DNA fluorescence probes based on side-chain chlorinated benzo[a]phenoxazinium chlorides

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Detalhes bibliográficos
Resumo:Several side chain chlorinated benzo[a]phenoxazinium chlorides functionalized with various types of terminals at the 5- and 9-amino positions of the heteroaromatic ring were used in photophysical studies with DNA. It was found that the functionalised terminal has a dramatic influence on the type of interaction with the amino group at the 9-amino position greatly promoting intercalation.
Autores principais:Raju, B. Rama
Outros Autores:Firmino, A. D. G.; Gonçalves, M. Sameiro T.; Coutinho, Paulo J. G.
Assunto:DNA probes Fluorescence Benzo[a]phenoxazine dyes
Ano:2012
País:Portugal
Tipo de documento:outro
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Several side chain chlorinated benzo[a]phenoxazinium chlorides functionalized with various types of terminals at the 5- and 9-amino positions of the heteroaromatic ring were used in photophysical studies with DNA. It was found that the functionalised terminal has a dramatic influence on the type of interaction with the amino group at the 9-amino position greatly promoting intercalation.