Publicação
Synthesis of Oxa-aza-macrocycle containing a naphthalimide unit: potential antioxidant activity of products
| Resumo: | [Extract] Macrocycles with heteroatoms such as nitrogen (1) and oxygen (2) have wide application in many areas of science. For example in medicine, aza-macrocycles [1] are used to sequester particle emitting radioisotopes for use with monoclonal antibody in radioimmunodiagnosis and radioimmunotherapy.[2] Also, aza-macrocycles and their metal complexes have been reported to have good anti-HIV activity.[3] The coordination chemistry of macrocycles with mixed nitrogen-oxygen donors has been thoroughly investigated over recent years. However, the coordination chemistry of macrocycles in which oxygen and nitrogen donors bonded to each other, such as in 3, is less known.[4]... |
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| Autores principais: | Duarte, Diana Catarina Moreira |
| Outros Autores: | Ferreira, Juliana Patrícia Moreira Marques; Fortes, A. Gil; Alves, Maria José Chão |
| Assunto: | Ciências Naturais::Ciências Químicas |
| Ano: | 2015 |
| País: | Portugal |
| Tipo de documento: | póster em conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | [Extract] Macrocycles with heteroatoms such as nitrogen (1) and oxygen (2) have wide application in many areas of science. For example in medicine, aza-macrocycles [1] are used to sequester particle emitting radioisotopes for use with monoclonal antibody in radioimmunodiagnosis and radioimmunotherapy.[2] Also, aza-macrocycles and their metal complexes have been reported to have good anti-HIV activity.[3] The coordination chemistry of macrocycles with mixed nitrogen-oxygen donors has been thoroughly investigated over recent years. However, the coordination chemistry of macrocycles in which oxygen and nitrogen donors bonded to each other, such as in 3, is less known.[4]... |
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