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Magnetic/plasmonic MnFe2O4/Au nanoparticles covered with lipid bilayers for applications in thermotherapy

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Detalhes bibliográficos
Resumo:In this work, three different types of magnetic/plasmonic nanoparticles were prepared: core-shell nanoparticles with a manganese ferrite core and a gold shell; plasmonic gold nanoparticles decorated with magnetic nanoparticles of manganese ferrite; and magnetic nanoparticles of manganese ferrite decorated with plasmonic gold nanoparticles. The structural, spectroscopic and magnetic properties of these nanoparticles were evaluated. In order to further develop applications in cancer therapy, the prepared mixed nanoparticles were covered with a lipid bilayer. The local heating capability of these nanosystems was tested through the quenching of rhodamine fluorescence incorporated in the lipid layer.
Autores principais:Matos, Joana Isabel Oliveira Gomes de
Outros Autores:Rodrigues, Ana Rita Oliveira; Almeida, B. G.; Araújo, João P.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.
Assunto:Magnetic nanoparticles Plasmonic nanoparticles Magnetoliposomes Cancer therapy Thermotherapy
Ano:2017
País:Portugal
Tipo de documento:póster em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:In this work, three different types of magnetic/plasmonic nanoparticles were prepared: core-shell nanoparticles with a manganese ferrite core and a gold shell; plasmonic gold nanoparticles decorated with magnetic nanoparticles of manganese ferrite; and magnetic nanoparticles of manganese ferrite decorated with plasmonic gold nanoparticles. The structural, spectroscopic and magnetic properties of these nanoparticles were evaluated. In order to further develop applications in cancer therapy, the prepared mixed nanoparticles were covered with a lipid bilayer. The local heating capability of these nanosystems was tested through the quenching of rhodamine fluorescence incorporated in the lipid layer.