Publicação
Identification of yield coefficients in an E. coli model : an optimal experimental design using genetic algorithms
| Resumo: | An optimal experimental design for yield coefficients estimation in an unstructured growth model of fed-batch fermentation of E. coli is presented. The feed profile is designed by optimisation of a scalar function based on the Fischer Information Matrix. A genetic algorithm is proposed as the optimisation method due to its efficiency and independence on the initial values. |
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| Autores principais: | Veloso, Ana C. A. |
| Outros Autores: | Rocha, I.; Ferreira, Eugénio C. |
| Assunto: | Optimisation Genetic algorithms Fisher information matrix Fed-batch fermentation E. coli Yield coefficients |
| Ano: | 2005 |
| País: | Portugal |
| Tipo de documento: | comunicação em conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | An optimal experimental design for yield coefficients estimation in an unstructured growth model of fed-batch fermentation of E. coli is presented. The feed profile is designed by optimisation of a scalar function based on the Fischer Information Matrix. A genetic algorithm is proposed as the optimisation method due to its efficiency and independence on the initial values. |
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