Publicação
Putting the focus on sleep quality: subjective sleep measures, actigraphy and brain correlates in ageing
| Resumo: | Sleep is a multidimensional phenomenon with a relevant role in the maintenance of organism homeostasis, overall well-being and optimal cognitive function. Throughout the lifespan, changes in sleep dimensions occur, namely on its timing, duration, architecture and quality. In what concerns to sleep quality, studies are highly heterogeneous; not only the tools used are extremely variable, but also the way this concept is defined. Thus, the present thesis aims at providing a thorough analysis on the meaning of sleep quality, contributing to the clarification of its definition. It also aims to determine the sleep patterns, routines and quality of Portuguese community-dwellers across the adult lifespan and determine the main predictors of self-reported sleep. It is also an aim to explore the association between a composite measure of sleep quality and brain correlates. For these purposes, a systematic review of the literature on sleep quality meaning was performed and three original studies developed considering a cross-sectional and/or a longitudinal approach. Portuguese community-dwellers within the adult lifespan (18 and more years) were recruited and self-reported sleep quality and psychological variables were assessed in the first two studies and in the third, neuroimaging information was also collected. Results show that sleep quality is a multidimensional concept that should integrate information from different settings (e.g. clinical measures such as the Pittsburgh Sleep Quality Index, and parameters that reflect the interpretation of lay individuals of it). Lay people interpretation of sleep quality seems to be stable across the adult lifespan and no differences between men and women are observed regarding the parameters reported. Poor subjective sleep quality is associated with decreases in functional and structural connectivity of specific brain networks, with an overlapping node in the middle left temporal region. Overall, the present work contributes for the clarification of sleep quality concept, enabling a better comparison between study results. Despite the contributions of this doctoral work to the body of literature, there are still avenues to be explored so that individuals can benefit from personalized sleep care, and physicians can better act on the subjective informations reported by their patients, feasibly taking advantages of the new technologies to better monitor sleep in ecological settings. |
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| Autores principais: | Amorim, Liliana Patrícia Carvalho |
| Assunto: | Actigraphy MRI PSQI Psychological Variables Subjective sleep quality Actigrafia Qualidade Subjetiva de Sono Variáveis psicológicas |
| Ano: | 2019 |
| País: | Portugal |
| Tipo de documento: | tese de doutoramento |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | Sleep is a multidimensional phenomenon with a relevant role in the maintenance of organism homeostasis, overall well-being and optimal cognitive function. Throughout the lifespan, changes in sleep dimensions occur, namely on its timing, duration, architecture and quality. In what concerns to sleep quality, studies are highly heterogeneous; not only the tools used are extremely variable, but also the way this concept is defined. Thus, the present thesis aims at providing a thorough analysis on the meaning of sleep quality, contributing to the clarification of its definition. It also aims to determine the sleep patterns, routines and quality of Portuguese community-dwellers across the adult lifespan and determine the main predictors of self-reported sleep. It is also an aim to explore the association between a composite measure of sleep quality and brain correlates. For these purposes, a systematic review of the literature on sleep quality meaning was performed and three original studies developed considering a cross-sectional and/or a longitudinal approach. Portuguese community-dwellers within the adult lifespan (18 and more years) were recruited and self-reported sleep quality and psychological variables were assessed in the first two studies and in the third, neuroimaging information was also collected. Results show that sleep quality is a multidimensional concept that should integrate information from different settings (e.g. clinical measures such as the Pittsburgh Sleep Quality Index, and parameters that reflect the interpretation of lay individuals of it). Lay people interpretation of sleep quality seems to be stable across the adult lifespan and no differences between men and women are observed regarding the parameters reported. Poor subjective sleep quality is associated with decreases in functional and structural connectivity of specific brain networks, with an overlapping node in the middle left temporal region. Overall, the present work contributes for the clarification of sleep quality concept, enabling a better comparison between study results. Despite the contributions of this doctoral work to the body of literature, there are still avenues to be explored so that individuals can benefit from personalized sleep care, and physicians can better act on the subjective informations reported by their patients, feasibly taking advantages of the new technologies to better monitor sleep in ecological settings. |
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