Publicação

Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes

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Detalhes bibliográficos
Resumo:Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.
Autores principais:Nebenzahl-Guimaraes, Hanna
Outros Autores:van Laarhoven, Arjan; Farhat, Maha R.; Koeken, Valerie A. C. M.; Mandemakers, Jornt J.; Zomer, Aldert; van Hijum, Sacha A. F. T.; Netea, Mihai G.; Murray, Megan; van Crevel, Reinout; van Soolingen, Dick
Assunto:Genetic Markers Immunity, Cellular Mycobacterium tuberculosis Phenotype tuberculosis transmission bacterial genomes immunology
Ano:2017
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.