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Synthesis and ion recognition studies of novel benzimidazol-5-yl-L-alanines

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Detalhes bibliográficos
Resumo:N-fluorenylmethoxycarbonyl-4-amino-phneylalanine and appropriate heterocyclic aldehydes were used in the synthesis of novel fluorescent unnatural amino acids, namely benzimidazol-5-yl-L-alanines. These new compounds were characterised by the usual spectroscopic techniques. The photophysical properties of the new amino acids were evaluated by UV-Vis absorption and fluorescence spectroscopy in acetonitrile. Interaction studies with biologically and analytically important ions such as Cu2+, Fe3+, Hg2+ and Pd2+, through spectrophotometric and spectrofluorimetric titrations were carried out to assess their potential as chemosensors.
Autores principais:Esteves, Cátia I. C.
Outros Autores:Rosa, Mayla E.; Raposo, M. Manuela M.; Costa, Susana P. G.
Assunto:Benzimidazole Thiophene Furan Amino acids Chemosensors Fluorescence
Ano:2015
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:N-fluorenylmethoxycarbonyl-4-amino-phneylalanine and appropriate heterocyclic aldehydes were used in the synthesis of novel fluorescent unnatural amino acids, namely benzimidazol-5-yl-L-alanines. These new compounds were characterised by the usual spectroscopic techniques. The photophysical properties of the new amino acids were evaluated by UV-Vis absorption and fluorescence spectroscopy in acetonitrile. Interaction studies with biologically and analytically important ions such as Cu2+, Fe3+, Hg2+ and Pd2+, through spectrophotometric and spectrofluorimetric titrations were carried out to assess their potential as chemosensors.