Publicação
Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications
| Resumo: | The success of bone tissue engineering (TE) strategies is strongly dependent on the development of new synthetic materials com- bining osteoconductive, osteoinductive and osteogenic properties. Recent studies suggest that biomaterials incorporating silanol groups promote and maintain osteogenesis with or without bio- logical stimuli. This study aims to evaluate the osteoconductivity and osteogenic properties of novel wet-spun fibre mesh scaffolds of SPCL (blend of starch with polycaprolactone) with or without superficial functionalized silanol (Si-OH) groups by seeding/culturing them with goat marrow stromal cells (GBMCs) |
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| Autores principais: | Rodrigues, M. T. |
| Outros Autores: | Leonor, I. B.; Viegas, C. A. A.; Dias, I. R.; Gomes, Manuela E.; Reis, R. L. |
| Assunto: | Goat marrow stromal cells Osteoconductive materials Silanol groups Starch-based polymers |
| Ano: | 2008 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | The success of bone tissue engineering (TE) strategies is strongly dependent on the development of new synthetic materials com- bining osteoconductive, osteoinductive and osteogenic properties. Recent studies suggest that biomaterials incorporating silanol groups promote and maintain osteogenesis with or without bio- logical stimuli. This study aims to evaluate the osteoconductivity and osteogenic properties of novel wet-spun fibre mesh scaffolds of SPCL (blend of starch with polycaprolactone) with or without superficial functionalized silanol (Si-OH) groups by seeding/culturing them with goat marrow stromal cells (GBMCs) |
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