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Biotechnological advancements, innovations and challenges for sustainable xylitol production by yeast

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Detalhes bibliográficos
Resumo:Xylitol is a sugar alcohol widely used as a sweetener in pharmaceutical and food industries, and also a valuable building block for the production of several other value-added chemicals. Biotechnological production of xylitol by yeast-based bioconversion processes has been gaining increasing attention as a promising alternative production route to current chemical production. This article includes an overview of the main natural xylitol producers and describes genetic engineering approaches to design Saccharomyces cerevisiae for an improved xylitol production, as well as the current advances and challenges in the valorization of lignocellulosic biomass for xylitol biosynthesis.
Autores principais:Sara Baptista
Outros Autores:Romani, Aloia Perez; Domingues, Lucília
Assunto:Added-value chemical Bioconversion Biotechnological production Lignocellulosic biomass Metabolic engineering Microbial cell factories Renewable feedstocks Saccharomyces cerevisiae Strain improvement Sweetener Xylitol Yeast
Ano:2021
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Xylitol is a sugar alcohol widely used as a sweetener in pharmaceutical and food industries, and also a valuable building block for the production of several other value-added chemicals. Biotechnological production of xylitol by yeast-based bioconversion processes has been gaining increasing attention as a promising alternative production route to current chemical production. This article includes an overview of the main natural xylitol producers and describes genetic engineering approaches to design Saccharomyces cerevisiae for an improved xylitol production, as well as the current advances and challenges in the valorization of lignocellulosic biomass for xylitol biosynthesis.