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Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems

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Resumo:The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.
Autores principais:Klein, Jaroslav
Outros Autores:Vicente, A. A.; Teixeira, J. A.
Assunto:Airlift Three-phase flow Hydrodynamic model Solids distribution Gas-liquid separator
Ano:2003
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.