Detalhes bibliográficos
| Resumo: | In this study metabolic footprinting was applied to evaluate the metabolic consequences of protein overproduction at slow growth conditions (μ = 0.1 h-1). The extracellular metabolites detected by gas chromatography-mass spectrometry characterized the metabolic footprints before and after the induction of the recombinant protein production (i.e. pre- and post-induction phases). Metabolic footprinting enabled the discrimination between the two growth phases and ex-posed significant metabolic alterations in the extracellular milieu during the re-combinant processes. |
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| Autores principais: | Carneiro, S. |
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| Outros Autores: | Villas-Bôas, S. G.; Rocha, I.; Ferreira, Eugénio C. |
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| Ano: | 2010 |
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| País: | Portugal |
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| Tipo de documento: | comunicação em conferência |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade do Minho |
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| Idioma: | inglês |
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| Origem: | RepositóriUM - Universidade do Minho |
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