Publicação
Magnetogels based on iron oxide nanoparticles and peptide hydrogels containing Naproxen and/or RGD
| Resumo: | In this work, iron oxide nanoparticles, with diameters around 12 nm, were synthesized by coprecipitation method in aqueous solution. These nanoparticles exhibit a superparamagnetic behavior, with a coercive field of 9.7 Oe and a blocking temperature of 118 K. The nanoparticles were successfully incorporated in peptide-based hydrogels containing naproxen (Npx) and/or RGD. The ability of these magnetogels to act as drug nanocarriers is being investigated, aiming at developing multifunctional therapeutic nanosystems. |
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| Autores principais: | Magalhães, Carlos A. B. |
| Outros Autores: | Rodrigues, Ana Rita Oliveira; Almeida, B. G.; Martins, J. A.; Coutinho, Paulo J. G.; Araújo, João P.; Ferreira, Paula M. T.; Castanheira, Elisabete M. S. |
| Assunto: | Magnetic nanoparticles Hydrogels Drug nanocarriers Targeted therapy |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | In this work, iron oxide nanoparticles, with diameters around 12 nm, were synthesized by coprecipitation method in aqueous solution. These nanoparticles exhibit a superparamagnetic behavior, with a coercive field of 9.7 Oe and a blocking temperature of 118 K. The nanoparticles were successfully incorporated in peptide-based hydrogels containing naproxen (Npx) and/or RGD. The ability of these magnetogels to act as drug nanocarriers is being investigated, aiming at developing multifunctional therapeutic nanosystems. |
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