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A new method for yeast phagocytosis analysis by flow cytometry

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Detalhes bibliográficos
Resumo:Herein we developed a method based on the quenching effect of propidium iodide over Sytox-Green fluorescence to assess yeast phagocytosis by flow cytometry. It allows accurate quantification of living from dead phagocytes; internalized from non-internalized cells, maintaining yeast fluorescence within phagocytes; and the different associations between phagocytes and fungal cells. (C) 2014 Elsevier B.V. All rights reserved.
Autores principais:Carneiro, Maria Catarina Santos
Outros Autores:Vaz, Catarina Oliveira; Pais, Célia; Sampaio, Paula; Pereira, Joana Isabel Carvalho
Assunto:Candida spp Flow cytometry Sytox green Propidium iodide Phagocytosis PAMPs
Ano:2014
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:Herein we developed a method based on the quenching effect of propidium iodide over Sytox-Green fluorescence to assess yeast phagocytosis by flow cytometry. It allows accurate quantification of living from dead phagocytes; internalized from non-internalized cells, maintaining yeast fluorescence within phagocytes; and the different associations between phagocytes and fungal cells. (C) 2014 Elsevier B.V. All rights reserved.