Detalhes bibliográficos
| Resumo: | "Staphylococcus epidermidis is a Gram-positive commensal bacterium found mainly in mucous membranes but also in sebaceous areas. It is considered an opportunistic pathogen associated with nosocomial infections. Indeed, S. epidermidis is the main cause of coagulase negative staphylococci infections associated with medical devices. This thesis aims to understand the impact of pH conditions which mimic the skin pH (5.5) and blood pH (7.4) in a S. epidermidis commensal strain (19N) biological processes and metabolic pathways. Proteomic studies were realized by nanoscale liquid chromatography-tandem mass spectrometry (nano LC-MS/MS) and metabolomic studies through nuclear magnetic resonance (NMR) in the whole cellular extract." |
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| Autores principais: | Santos, Susana Isabel Duarte dos |
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| Assunto: | Staphylococcus epidermidis infection process proteomic metabolomic |
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| Ano: | 2019 |
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| País: | Portugal |
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| Tipo de documento: | dissertação de mestrado |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade Nova de Lisboa |
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| Idioma: | inglês |
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| Origem: | Repositório Institucional da UNL |
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