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In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance

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Detalhes bibliográficos
Resumo:"BACKGROUND AND AIMS: Although indole-3-propionic acid (IPA) has been shown to exhibit preventive effects against type 2 diabetes (T2D), nothing is known regarding its ability to restore T2D-associated hallmarks. As such, this study aimed to assess the ability of IPA to reverse the metabolic phenotype of insulin-resistant 3T3-L1 adipocytes.(...)"
Autores principais:Franco, IS
Assunto:adipocytes glucose uptake hyperinsulinemia insulin resistance lipolysis indole-3-propionic acid
Ano:2024
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:"BACKGROUND AND AIMS: Although indole-3-propionic acid (IPA) has been shown to exhibit preventive effects against type 2 diabetes (T2D), nothing is known regarding its ability to restore T2D-associated hallmarks. As such, this study aimed to assess the ability of IPA to reverse the metabolic phenotype of insulin-resistant 3T3-L1 adipocytes.(...)"