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Molecular and Cellular Investigation of Malate:quinone oxidoreductases from Staphylococcus aureus

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Detalhes bibliográficos
Resumo:"Staphylococcus aureus are opportunistic pathogens and represent one of the most frequent causes for community acquired and nosocomial infections. Over time, S. aureus has developed several mechanisms which led to the selection of increasingly resistant strains. These potentially lethal bacterial pathogens have become a major public health threat, being urgent the development of new drugs against this worldwide problem. However, and intriguingly many fundamental aspects of S. aureus have escaped attention, such as its energy metabolism and respiratory enzymes. We aim to contribute to this knowledge by exploring malate:quinone oxidoreductases at molecular and cellular levels.(...)"
Autores principais:Gonçalves, Joana Lisboa da Silva
Assunto:Energy metabolism respiratory enzymes; malate:quinone oxidoreductases respiratory chain
Ano:2017
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:"Staphylococcus aureus are opportunistic pathogens and represent one of the most frequent causes for community acquired and nosocomial infections. Over time, S. aureus has developed several mechanisms which led to the selection of increasingly resistant strains. These potentially lethal bacterial pathogens have become a major public health threat, being urgent the development of new drugs against this worldwide problem. However, and intriguingly many fundamental aspects of S. aureus have escaped attention, such as its energy metabolism and respiratory enzymes. We aim to contribute to this knowledge by exploring malate:quinone oxidoreductases at molecular and cellular levels.(...)"