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Formate metabolism in sulfate reducing bacteria

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Resumo:Sulfate reduction is a very ancient metabolic process and it is responsible for more than 50% of carbon mineralization in anaerobic marine sediments. Sulfate-reducing organisms (SRO) are able to couple the reduction of sulfate to the oxidation of organic compounds, such as lactate or formate, or molecular hydrogen (H2), in order to obtain energy for cell synthesis and growth. Despite recent significant advances, a lot remains to be known about the mechanisms for energy conservation in SRO, and the specific components involved in those mechanisms. Formate and hydrogen are two abundant metabolites in SRO habitats, usually formed as fermentation products of other organisms. However, while the role of hydrogen and hydrogenases in anaerobic metabolism has been intensively studied over the years, formate has not received the same attention as an equally important metabolite.(...)
Autores principais:Silva, Sofia M. da
Ano:2011
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:Sulfate reduction is a very ancient metabolic process and it is responsible for more than 50% of carbon mineralization in anaerobic marine sediments. Sulfate-reducing organisms (SRO) are able to couple the reduction of sulfate to the oxidation of organic compounds, such as lactate or formate, or molecular hydrogen (H2), in order to obtain energy for cell synthesis and growth. Despite recent significant advances, a lot remains to be known about the mechanisms for energy conservation in SRO, and the specific components involved in those mechanisms. Formate and hydrogen are two abundant metabolites in SRO habitats, usually formed as fermentation products of other organisms. However, while the role of hydrogen and hydrogenases in anaerobic metabolism has been intensively studied over the years, formate has not received the same attention as an equally important metabolite.(...)